Your shopping cart is empty!
Anti-TRAP1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Heat shock protein 75 kDa, mitochondrial |
Synonyms: | HSP75, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP-1, Trap1, HSP90L |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TRAP1 |
Uniprot ID: | Q9CQN1 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion |
Product Usage Information
IHC/IF | Human, Mouse, Rat | 1: 150-1: 600 | heart, kidney, skeletal muscle |
Background
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
Images
| Immunohistochemistry analysis of paraffin embedded human kidney using TRAP1 (GB115580) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using TRAP1 (GB115580) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded mouse heart using TRAP1 (GB115580) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded mouse skeletal muscle using TRAP1 (GB115580) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded mouse skeletal muscle using TRAP1 (GB115580) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded rat heart using TRAP1 (GB115580) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded rat testis using TRAP1 (GB115580) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
