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Anti-TROVE2/SS-A Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TROVE2/SS-A rabbit polyclonal antibody |
Gene Name: | 60 kDa SS-A/Ro ribonucleoprotein |
Synonyms: | 60 kDa ribonucleoprotein Ro, 60 kDa Ro protein, Ro 60 kDa autoantigen, RO60, RoRNP, Sjoegren syndrome antigen A2, SS A, SSA2, TROVE domain family member 2, TROVE2 |
Immunogen: | Recombinant protein corresponding to Mouse TROVE2/SS-A |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 60 kDa |
Observed MW. | 60 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 1000-1: 2000 | brain |
Background
TROVE2, also named as RO60 or RoRNP, is a 538 amino acid protein, which is localized in cytoplasmic mRNP granules containing untranslated mRNAs. TROVE2 as a RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. TROVE2 may stabilize some of these RNAs and protect them from degradation. TROVE2 binds to endogenous Alu retroelements which are induced by type I IFN and stimulate porinflammaotry cytokine secretion.
Images
 | Western blot analysis of TROVE2 (GB113865) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
