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Anti-TRPA1/TSA Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Transient receptor potential cation channel subfamily A member 1 |
Synonyms: | ANKTM1, TRPA1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TRPA1/TSA |
Uniprot ID: | Q8BLA8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 128 kDa / 120-130 kDa |
Product Usage Information
WB | Human | 1: 300-1: 600 | HeLa |
Background
Receptor-activated non-selective cation channel involved in pain detection and possibly also in cold perception, oxygen concentration perception, cough, itch, and inner ear function . Shows 8-fold preference for divalent over monovalent cations. Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of irritants, such as allylthiocyanate (AITC) found in mustard oil or wasabi, cinnamaldehyde, diallyl disulfide (DADS) from garlic, and acrolein, an irritant from tears gas and vehicule exhaust fumes. Acts also as an ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana.
Images
| Western blot analysis of TRPA1 (GB114711) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
