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Anti-TRPC3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TRPC3 rabbit polyclonal antibody |
Gene Name: | Short transient receptor potential channel 3 |
Synonyms: | TrpC3, Receptor-activated cation channel TRP3, Transient receptor protein 3, TRP-3, mTrp3, rp-related protein 3, Trpc3, Trp3, Trrp3 |
Immunogen: | Recombinant protein corresponding to Mouse TRPC3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell Membrane |
Uniprot ID: | Q9QZC1, Q9JMI9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | brain, epencephalon, ovary |
Background
The TRPC3 is thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol 1,4,5-triphosphate receptors (ITPR) with bound IP3 (By similarity). May also be activated by internal calcium store depletion.
Images
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Immunohistochemistry of paraffin embedded mouse brain using TRPC3 (GB111207) at dilution of 1:3600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse epencephalon using TRPC3 (GB111207) at dilution of 1:3600 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using TRPC3 (GB111207) at dilution of 1:3600 (400x lens) |
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Immunohistochemistry of paraffin embedded rat epencephalon using TRPC3 (GB111207) at dilution of 1:3600 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using TRPC3 (GB111207) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded rat ovary using TRPC3 (GB111207) at dilution of 1:1400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
