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Anti-TTBK1 Rabbit pAb (100 μl)
| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TTBK1 rabbit polyclonal antibody |
Gene Name: | Tau-tubulin kinase 1 |
Synonyms: | KIAA1855, TTBK1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TTBK1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 142 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q6PCN3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse | 1: 300-1: 800 | brain, heart, testis |
Background
TTBK1 (tau tubulin kinase 1), also known as BDTK (brain-derived tau kinase), is a 1,321 amino acid protein that contains one protein kinase domain and belongs to the serine/threonine protein kinase family. Localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord, TTBK1 functions as a serine/threonine kinase that can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Specifically, TTBK1 uses divalent cations, such as magnesium and manganese, to catalyze the ATP-dependent transfer of a phosphate group onto Tau, creating a phosphoprotein and ADP.
Images
 | Western blot analysis of TTBK1 (GB113900) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
