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Anti-Talin 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Talin 1 rabbit polyclonal antibody |
Gene Name: | Talin-1 |
Synonyms: | Tln1, TLN1, ILWEQ, TLN, Talin 1, talin-1 |
Immunogen: | Recombinant protein corresponding to Mouse Talin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 270 kDa |
Observed MW. | 270 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | HeLa, NIH3T3, PC12, HepG2, HUVEC |
Background
Talin-1 is ubiquitously expressed, and is localized to costamere structures in cardiac and skeletal muscle cells, and to focal adhesions in smooth muscle and non-muscle cells. Talin-1 functions to mediate cell-cell adhesion via the linkage of integrins to the actin cytoskeleton and in the activation of integrins. Altered expression of talin-1 has been observed in patients with heart failure, however no mutations in TLN1 have been linked with specific diseases.
Images
 | Western blot analysis of Talin (GB11675) at dilution of 1: 500 |
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Western blot analysis of Talin (GB11675) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
