Reactivity: | H,R |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Thymidylate synthase |
Synonyms: | HsT422, Thymidylate synthase, thymidylate synthetase, TMS, TS, TSase, TYMS |
Immunogen: | Recombinant protein corresponding to Human Thymidylate synthase |
Uniprot ID: | P04818 |
Isotype: | IgG2a,κ |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. / Observed MW. | 36 kDa / 36 kDa |
Product Usage Information
WB | Human, Rat | 1: 500-1: 1000 | HeLa, C6, Jurkat, Hep G2, MCF7 |
Background
Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Images
Western blot analysis of Thymidylate (GB122055) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |