Reactivity: | M,R & M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Tropomyosin 1 (alpha) rabbit polyclonal |
Gene Name: | Tropomyosin alpha-1 chain |
Synonyms: | Alpha tropomyosin, C15orf13, CMD1Y, HTM alpha, TMSA, TPM1, Tropomyosin 1, tropomyosin 1 (alpha), Tpm-1, Tpma |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Tropomyosin 1 (alpha) |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Cytoskeleton |
Predicted MW. | 33 kDa |
Observed MW. | 113708 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 2000-1: 4000 | heart, skeletal muscle |
IHC | Mouse, Rat | 1: 800-1: 1600 | heart, uterus, tongue |
Background
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Images
Western blot analysis of TPM1 (GB113708) at dilution of 1: 400 | |
Immunohistochemistry analysis of paraffin-embedded mouse heart using TMP1 (GB113708) at dilution of 1: 1600 | |
Immunohistochemistry analysis of paraffin-embedded mouse uterus using TMP1 (GB113708) at dilution of 1: 1600 | |
Immunohistochemistry analysis of paraffin-embedded mouse tongue using TMP1 (GB113708) at dilution of 1: 1600 | |
Immunohistochemistry analysis of paraffin-embedded rat tongue using TMP1 (GB113708) at dilution of 1: 1600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |