Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | UBE2O rabbit polyclonal antibody |
Gene Name: | (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O |
Synonyms: | E2/E3 hybrid ubiquitin-protein ligase UBE2O, Ubiquitin-conjugating enzyme E2 O, Ubiquitin-conjugating enzyme E2 of 230 kDa, Ubiquitin-protein ligase O, Ube2o, Kiaa1734, Ubiquitin carrier protein O |
Immunogen: | Recombinant protein corresponding to Mouse UBE2O |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 141 kDa |
Observed MW. | 220 kDa |
Uniprot ID: | Q6ZPJ3 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 500-1: 1000 | brain, skeletal muscle |
Background
UBE20, also known as E2-230K, is a 1,292 amino acid member of the uniquitin-conjugating enzyme family that is involved in protein modification. Expressed predominately in heart and skeletal muscle, UBE2O functions to catalyze the ATP-dependent covalent attachment of ubiquitin to select proteins, thereby targeting the ubiquitinated proteins for proteasomal degradation.
Images
Western blot analysis of UBE2O (GB112665) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |