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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UCP2 rabbit polyclonal antibody |
Gene Name: | Mitochondrial uncoupling protein 2 |
Synonyms: | UCP2, BMIQ4, SLC25A8, UCPH, uncoupling protein 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse UCP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Mitochondrion inner membrane |
Uniprot ID: | P70406, P55851, P56500 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:200-1:600 | lung, lymphoma, spleen |
Background
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells.
Images
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Immunohistochemistry of paraffin embedded human lymphoma using UCP2 (GB11377) at dilution of 1:300 (400x lens) |
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Immunofluorescence of paraffin embedded mouse lung using UCP2 (GB11377) at dilution of 1:200 (400x lens) |
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Immunofluorescence of paraffin embedded mouse spleen using UCP2 (GB11377) at dilution of 1:200 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
