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Anti-UNC80 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | UNC80 rabbit polyclonal |
Gene Name: | Protein unc-80 homolog |
Synonyms: | mUNC-80, Unc80, Kiaa1843, C2orf21, |
Immunogen: | Recombinant protein corresponding to Mouse UNC80 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 364 kDa |
Observed MW. | 364 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 1000-1: 2000 | U-251 MG |
Background
The protein encoded by this gene is a component of a voltage-independent 'leak' ion-channel complex, in which it performs essential functions, such as serving as a bridge between two other components (sodium leak channel non-selective and UNC79) and as a scaffold for Src kinases. Leak channels play an importnat role in establishment and maintenance of resting membrane potentials in neurons. Mutations in this gene are associated with congenital infantile encephalopathy, intellectual disability and growth issues.
Images
| Western blot analysis of UNC80 (GB113353) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
