Reactivity: | H & M |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | UBX domain-containing protein 4 |
Synonyms: | Erasin, UBX domain-containing protein 2, Ubxn4, Ubxd2, Ubxdc1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Ubxn4 |
Uniprot ID: | Q8VCH8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 56 kDa / 64 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HepG2, HeLa, 293T |
ICC/IF | Mouse | 1: 50-1: 200 | NIH-3T3 |
Background
UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP) and promotes ER-associated protein degradation (ERAD). In addition, erasin may be involved in Alzheimer’s disease, as it is known to accumulate in neurofibrillary degenerating neurons in patients with Alzheimer’s disease.
Images
Western blot analysis of UBXD2 (GB111465) at dilution of 1: 500 |
|
Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using Ubxn4(GB111465) at dilution of 1: 50-1: 200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |