Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Vinculin |
Synonyms: | Metavinculin, Vcl, CMD1W, CMH15, MVCL, MV, VINC |
Immunogen: | Recombinant protein corresponding to Human Vinculin |
Uniprot ID: | P18206 |
Isotype: | IgG2a,k |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 117 kDa / 124 kDa |
Product Usage Information
WB | Human, Mouse ,Rat | 1: 500-1: 1000 | lung , NIH/3T3 , uterine |
Background
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion.
Images
WB analysis of Vinculin(GB121328). Sample: Protein treated by RIPA Lysis Buffer (G2002). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |