Your shopping cart is empty!
Anti-XRCC6BP1/KUB3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | XRCC6BP1/KUB3 rabbit polyclonal |
Gene Name: | Mitochondrial inner membrane protease ATP23 homolog |
Synonyms: | XRCC6-binding protein 1, Atp23, Xrcc6bp1, ATP23, Ku70 binding protein 3, KUB3 |
Immunogen: | Recombinant protein corresponding to Mouse XRCC6BP1/KUB3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 22 kDa |
Observed MW. | 30 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | brain, testis |
Background
The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blot analysis of KUB3 (GB113036) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
