Reactivity: | R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ZBTB20 rabbit polyclonal |
Gene Name: | Zinc finger and BTB domain-containing protein 20 |
Synonyms: | BTB/POZ domain zinc finger factor HOF, Zinc finger protein 288, Zbtb20, Zfp288, DPZF, HOF, ODA 8S |
Immunogen: | Recombinant protein corresponding to Mouse ZBTB20 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 6000-1: 12000 | prefrontal lobe, heart |
Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZBTB20 (zinc finger and BTB domain containing 20), also known as HOF, DPZF, ODA-8S or ZNF288, is a 741 amino acid protein that localizes to the nucleus and contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed in thymus, spleen, lymph node and fetal liver, ZBTB20 exists as either a monomer or a homodimer that is thought to function as a transcription factor, playing a role in hematopoiesis, oncogenesis and immune responses. Multiple isoforms of ZBTB20 exist due to alternative splicing events.
Images
Immunohistochemistry analysis of paraffin-embedded rat prefrontal lobe using ZBTB20 (GB112977) at dilution of 1: 12000 | |
Immunohistochemistry analysis of paraffin-embedded rat heart using ZBTB20 (GB112977) at dilution of 1: 12000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |