| Reactivity: | R | 
| Applications: | IHC | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | ZBTB20 rabbit polyclonal  | 
Gene Name:  | Zinc finger and BTB domain-containing protein 20  | 
Synonyms:  | BTB/POZ domain zinc finger factor HOF, Zinc finger protein 288, Zbtb20, Zfp288, DPZF, HOF, ODA 8S  | 
Immunogen:  | Recombinant protein corresponding to Mouse ZBTB20  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Nucleus  | 
Uniprot ID:  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive tissue  | 
IHC  | Rat  | 1: 6000-1: 12000  | prefrontal lobe, heart  | 
Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZBTB20 (zinc finger and BTB domain containing 20), also known as HOF, DPZF, ODA-8S or ZNF288, is a 741 amino acid protein that localizes to the nucleus and contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed in thymus, spleen, lymph node and fetal liver, ZBTB20 exists as either a monomer or a homodimer that is thought to function as a transcription factor, playing a role in hematopoiesis, oncogenesis and immune responses. Multiple isoforms of ZBTB20 exist due to alternative splicing events.
Images
  | Immunohistochemistry analysis of paraffin-embedded rat prefrontal lobe using ZBTB20 (GB112977) at dilution of 1: 12000  | 
  | Immunohistochemistry analysis of paraffin-embedded rat heart using ZBTB20 (GB112977) at dilution of 1: 12000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |