Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | RING finger protein 112 |
Synonyms: | BFP, ring finger protein 112, RNF112, ZNF179 |
Immunogen: | Recombinant protein corresponding to Mouse ZNF179/BFP |
Uniprot ID: | Q96DY5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 71 kDa / 70 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 800 | brain, hippocampus |
Background
E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins . Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage.
Images
Western blot analysis of ZNF179/BFP (GB114245) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |