Reactivity: | H,M,R,Rabbit & H,M,R,Rabbit |
Applications: | WB & IHC/IF |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Actin, aortic smooth muscle |
Synonyms: | Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTA2, ACTSA, ACTVS, GIG46 |
Immunogen: | corresponding to human α-SMA |
Uniprot ID: | P62736 |
Isotype: | IgM |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm › cytoskeleton |
Predicted MW. / Observed MW. | 42 kDa / 42 kDa |
Product Usage Information
WB | Human, Mouse, Rat, Rabbit | 1: 500-1: 2000 | liver, lung, kidney, heart |
IHC/IF | Human, Mouse, Rat, Rabbit | 1: 100-1: 2000 | liver, lung, kidney, heart |
Background
Alpha-actin-2 also known as actin, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA).Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.
Images
Immunohistochemistry analysis of paraffin-embedded human kidney using α-SMA(GB13044) at dilution of 1:500. |
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Immunohistochemistry analysis of paraffin-embedded rat heart using α-SMA(GB13044) at dilution of 1:500. |
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Immunohistochemistry analysis of paraffin-embedded mouse liver using α-SMA(GB13044) at dilution of 1:500. |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |