Your shopping cart is empty!
Anti-beta 2 Microglobulin Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | beta 2 Microglobulin rabbit polyclonal antibody |
Gene Name: | Beta-2-microglobulin |
Synonyms: | Beta-2-microglobulin form pI 5.3, B2M, CDABP0092, HDCMA22P |
Immunogen: | Recombinant protein corresponding to Mouse beta 2 Microglobulin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 14 kDa |
Observed MW. | 14 kDa |
Uniprot ID: | P61769 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 500-1: 1000 | Jurkat, HepG2, Raji |
Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Images
|
|
Western blot analysis of β2-Microglobulin (GB111119) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
