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Anti-beta TRCP2/HOS Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | β-TRCP2 rabbit polyclonal antibody |
Gene Name: | F-box/WD repeat-containing protein 11 |
Synonyms: | Fbxw11, FBXW11, BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, F-box and WD repeat domain containing 11, β-TRCP2 |
Immunogen: | Recombinant protein corresponding to Mouse β-TRCP2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q9UKB1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 150-1: 1000 | breast cancer, colon cancer, liver cancer, renal cancer, thyroid gland |
Background
βTrCP2 (beta-transducin repeat containing protein 2; also known as Fbxw11 or HOS) is a protein encoded by the FBXW11 gene. The protein is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation -dependent ubiquitination.
Images
 | Immunohistochemistry of paraffin embedded human breast cancer using btrcp (GB11827) at dilution of 1:500 (400x lens) |
 | Immunohistochemistry of paraffin embedded human liver cancer using btrcp (GB11827) at dilution of 1:500 (400x lens) |
 | Immunohistochemistry of paraffin embedded human thyroid gland using btrcp (GB11827) at dilution of 1:500 (400x lens) |
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Immunofluorescence of paraffin embedded human breast cancer using btrcp (GB11827) at dilution of 1:300 (400x lens) |
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Immunofluorescence of paraffin embedded human colon cancer using btrcp (GB11827) at dilution of 1:300 (400x lens) |
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Immunofluorescence of paraffin embedded human renal cancer using btrcp (GB11827) at dilution of 1:300 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
