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Anti-c-Fos Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | c-Fos rabbit polyclonal antibody |
Gene Name: | Proto-oncogene c-Fos |
Synonyms: | FOS, AP-1, C-p55, Fos proto-oncogene, AP-1 transcription factor subunit |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human c-Fos |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 62 kDa |
Uniprot ID: | P01100 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1:500-1:1000 | HeLa, NIH/3T3, PC12, Raw264.7 |
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Images
| Western blot analysis of (GB114125) at dilution of 1: 1000 Lane1: HeLa untreated, whole cell lysate Lane2: HeLa starved overnight, then treated with 200 nM TPA for 4 hours, whole cell lysate Lane3: NIH3T3 untreated, whole cell lysate Lane4: NIH3T3 starved overnight, then treated with 200 nM TPA for 4 hours, whole cell lysate Lane5: Raw264.7 untreated, whole cell lysate Lane6: Raw264.7 starved overnight, then treated with 200 nM TPA for 4 hours, whole cell lysate Lane7: PC12 untreated, whole cell lysate Lane8: PC12 starved overnight, then treated with 200 nM TPA for 4 hours, whole cell lysate |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
