Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | c-Jun rabbit polyclonal antibody |
Gene Name: | Transcription factor AP-1 |
Synonyms: | JUN, AP-1, AP1, c-Jun, Jun proto-oncogene, AP-1 transcription factor subunit |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse c-JUN |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | P05412, P05627, P17325 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 1000-1: 4000 | brain, kidney, skin, stomach, testis |
Background
c-Jun is a protein that in humans is encoded by the JUN gene. c-Jun in combination with c-Fos, forms the AP-1early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the JNK pathway but has also a phosphorylation-independent function. c-jun knockout is lethal, but transgenic animalswith a mutated c-jun that cannot be phosphorylated (termed c-junAA) can survive.
Images
Immunohistochemistry of paraffin embedded human stomach using C-JUN (GB11071) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse kidney using C-JUN (GB11071) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat kidney using C-JUN (GB11071) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse skin using C-JUN (GB11071) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using C-JUN (GB11071) at dilution of 1:2000 (400x lens) | |
Immunofluorescence of paraffin embedded rat brain using C-JUN (GB11071) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |