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| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | cPLA2 rabbit polyclonal antibody |
Gene Name: | Cytosolic phospholipase A2 |
Synonyms: | PLA2G4A, PLA2G4, cPLA2-alpha, cPLA2, Phospholipase A2 group IVA |
Immunogen: | Recombinant protein corresponding to Mouse cPLA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 85 kDa |
Observed MW. | 85 kDa |
Uniprot ID: | P47712, P47713, P50393 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, spleen, lung |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | bone, hepatitis, liver, lung, pneumonia, splenitis |
Background
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor.
Images
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Western blot analysis of CPLA2 (GB11551) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded rat liver using CPLA2 (GB11551) at dilution of 1: 2000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lung using CPLA2 (GB11551) at dilution of 1: 2000 (400x lens) |
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Immunofluorescence of paraffin embedded mouse pneumonia using CPLA2 (GB11551) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse splenitis using CPLA2 (GB11551) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded rat bone using CPLA2 (GB11551) at dilution of 1: 500 (400x lens) |
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Immunofluorescence of paraffin embedded rat hepatitis using CPLA2 (GB11551) at dilution of 1: 500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
