Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | eIF5A2 rabbit polyclonal antibody |
Gene Name: | Eukaryotic translation initiation factor 5A-2 |
Synonyms: | eIF-5A-2, eIF-5A2, Eukaryotic initiation factor 5A isoform 2, Eif5a2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse eIF5A2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q8BGY2 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 250-1: 1200 | brain, kidney |
Background
This gene has an important function at the level of mRNA turnover, mRNA-binding protein involved in translation elongation. probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
Images
Immunohistochemistry of paraffin embedded mouse brain using eIF5A2 (GB111983) at dilution of 1:300 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse kidney using eIF5A2 (GB111983) at dilution of 1:250 (400x lens) | |
Immunofluorescence of paraffin embedded mouse brain using eIF5A2 (GB111983) at dilution of 1:300 (400x lens) | |
Immunofluorescence of paraffin embedded mouse kidney using eIF5A2 (GB111983) at dilution of 1:300 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |