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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Nitric oxide synthase, endothelial |
Synonyms: | NOS3, ECNOS, eNOS, nitric oxide synthase 3 |
Immunogen: | Recombinant protein corresponding to Human eNOS |
Uniprot ID: | P29474 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 133 kDa / 140 kDa |
Product Usage Information
WB | Human, Mouse | 1: 300-1: 1000 | HMUVC, bEnd.3 |
Background
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway . NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.; [Isoform eNOS13C]: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Images
| Western blot analysis of ENOS (GB115277) at dilution of 1:300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
