Reactivity: | H,M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | hnRNP M1-M4 rabbit polyclonal antibody |
Gene Name: | Heterogeneous nuclear ribonucleoprotein M |
Synonyms: | hnRNP M, HNRNPM, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, CEAR, CEA receptor, N acetylglucosamine receptor 1, hnRNA binding protein M4 |
Immunogen: | Recombinant protein corresponding to Mouse hnRNP M1-M4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. | 78 kDa |
Observed MW. | 78 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 1000-1: 3000 | brain, testis |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | ileum, cerebellum, heart, testis |
Background
HNRNPM, also named as NAGR1, is a 730 amino acid protein, which localizes in nucleus. HNRNPM as a pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. HNRNPM is Involved in splicing. HNRNPM acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. HNRNPM exists two isoforms with MV 77 kDa and 73 kDa.
Images
Western blot analysis of HNRNPM (GB113866) at dilution of 1: 3000 | |
Immunohistochemistry analysis of paraffin-embedded mouse ileum using HNRNPM (GB113866) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using HNRNPM (GB113866) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat heart using HNRNPM (GB113866) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat testis using HNRNPM (GB113866) at dilution of 1: 4000 | |
Immunofluorescent analysis of paraformaldehyde-fixed mouse ileum using HNRNPM (GB113866) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |