Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ApoER2 rabbit polyclonal antibody |
Gene Name: | Low-density lipoprotein receptor-related protein 8 |
Synonyms: | LRP-8, Apolipoprotein E receptor 2, Apoer2, LDL Receptor Related Protein 8 |
Immunogen: | Recombinant protein corresponding to Mouse ApoER2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 110 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q14114, Q924X6 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, testis, liver |
Background
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder.
Images
Western blot analysis of APOER2 (GB112068) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |