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Anti-Apolipoprotein A I Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Apolipoprotein A I rabbit polyclonal antibody |
Gene Name: | Apolipoprotein A-I |
Synonyms: | Apo-AI, ApoA-I, Apolipoprotein A1, Apoa1, Truncated apolipoprotein A-I, AIBP, Proapolipoprotein A-I, Apolipoprotein A I binding protein |
Immunogen: | Recombinant protein corresponding to Mouse Apolipoprotein A I |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | Q00623, P04639 |
Applications
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1900-1: 3800 | liver, small intestine |
Background
ApoA1 is a major protein component of high density lipoproteins (HDL) which is associated with reversed cholesterol transport, lipid/cholesterol binding, lecithin/cholesterol acyltransferase (LCAT) activation and specific receptors binding. ApoA1 promotes cholesterol efflux from tissues to the liver for excretion, and it’s a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects of ApoA1 cause low HDL level and systemic non-neuropathic amyloidosis. Serum concentration of ApoA1 is inversely related to the risk of developing atherosclerosis.
Images
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Immunohistochemistry of paraffin embedded mouse liver using AP0A1 (GB111356) at dilution of 1:1900 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse small intestine using AP0A1 (GB111356) at dilution of 1:1900 (400x lens) |
| Immunohistochemistry of paraffin embedded rat liver using AP0A1 (GB111356) at dilution of 1:1900 (400x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using AP0A1 (GB111356) at dilution of 1:1900 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
