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Anti-Aquaporin 3 Mouse mAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Aquaporin-3 |
Synonyms: | AQP3, AQP-3, GIL, aquaporin 3 (Gill blood group) |
Immunogen: | Recombinant protein corresponding to Mouse Aquaporin 3 |
Uniprot ID: | Q8R2N1 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | kidney |
Background
Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells. In the kidney, AQP3 is regulated by vasopressin (ADH). This protein is also a determinant for the GIL blood group system. Suberoylanilide hydroxamic acid (SAHA) (a HDAC inhibitor) increases expression of aquaporin-3 in normal skin cells (keratinocytes).
Images
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Immunohistochemistry of paraffin embedded mouse kidney using AQP3 (GB12533) at dilution of 1: 2000 (250x lens) |
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Immunohistochemistry of paraffin embedded rat kidney using AQP3 (GB12533) at dilution of 1: 2000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
