Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | B4GALT5 rabbit polyclonal |
Gene Name: | Beta-1,4-galactosyltransferase 5 |
Synonyms: | Beta4Gal-T5, b4Gal-T5, Lactosylceramide synthase, LacCer synthase, B4galt5, Bgt-5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse B4GALT5 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 45 kDa |
Observed MW. | 45 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | liver |
Background
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) . LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation . Plays a role in the glycosylation of BMPR1A and regulation of its protein stability . Essential for extraembryonic development during early embryogenesis .
Images
Western blot analysis of B4GALT5 (GB112912) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |