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Anti-BRCC45/BRE Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BRCC45/BRE rabbit polyclonal antibody |
Gene Name: | BRISC and BRCA1-A complex member 2 |
Synonyms: | BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, Brain and reproductive organ-expressed protein, Babam2, Bre, BRCC4, BRCC45 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse BRCC45/BRE |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q9NXR7, Q8K3W0, Q6P7Q1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 100-1: 500 | brain, embryonic mouse, glioma, pancreas, placenta |
Background
BRE, also named as BRCC45, is a death receptor-associated antiapoptotic protein, which is also involved in DNA-damage repair, and K63-specific deubiquitination. BRE and its XIAP-sustaining mechanism could represent novel targets for anti-cancer therapy. BRE may regulate TNF-alpha signaling through its interactions with TNFRSF1A. It plays a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. BRE gene has four isoforms with MW 42-47 kDa.
Images
| Immunohistochemistry of paraffin embedded human glioma using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunohistochemistry of paraffin embedded human placenta using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse brain using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse brain using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse pancreas using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse placenta using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunohistochemistry of paraffin embedded rat pancreas using BRE (GB112384) at dilution of 1:100 (400x lens) |
| Immunofluorescence of paraffin embedded human glioma using BRE (GB112384) at dilution of 1:250 (400x lens) |
| Immunofluorescence of paraffin embedded mouse brain using BRE (GB112384) at dilution of 1:250 (400x lens) |
| Immunofluorescence of paraffin embedded mouse embryonic mouse using BRE (GB112384) at dilution of 1:250 (400x lens) |
| Immunofluorescence of paraffin embedded mouse pancreas using BRE (GB112384) at dilution of 1:250 (400x lens) |
| Immunofluorescence of paraffin embedded rat brain using BRE (GB112384) at dilution of 1:250 (400x lens) |
| Immunofluorescence of paraffin embedded rat placenta using BRE (GB112384) at dilution of 1:250 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
