Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | BTF rabbit polyclonal antibody |
Gene Name: | Bcl-2-associated transcription factor 1 |
Synonyms: | BCLAF1, bK211L9.1, BTF, Kiaa0164 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse BTF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q8K019 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | brain, heart |
Background
BCLF1, also named as Bcl-2-associated transcription factor 1, is a 920 amino acid protein, which Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA. BCLF1 as a death-promoting transcriptional repressor may be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. The calculated molecular weight of BCLF1 is a 110 kDa, but the modified BCLF1 protein is about 140-150 kDa.
Images
Immunohistochemistry of paraffin embedded mouse heart using BCLAF1 (GB111962) at dilution of 1:2000 (300x lens) | |
Immunohistochemistry of paraffin embedded mouse brain using BCLAF1 (GB111962) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |