Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | BTNL2 rabbit polyclonal antibody |
Gene Name: | Butyrophilin-like protein 2 |
Synonyms: | Btnl2, Gm315, Ng9, BTL-II, butyrophilin-like 2 (MHC class II associated), Butyrophilin-like protein 2, butyrophylin-like MHC class II associated, Btl2, BTLN2, BTN7, HSBLMHC1, SS2 |
Immunogen: | Recombinant protein corresponding to Mouse BTNL2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 51 kDa |
Observed MW. | 65 kDa |
Uniprot ID: | Q9UIR0, O70355, Q6MG97 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, kidney, small intestine |
Background
BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
Images
Western blot analysis of BTNL2 (GB111525) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |