Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | RNA-splicing ligase RtcB homolog |
Synonyms: | C22orf28, FAAP, HSPC117, RtcB, RtcB-Specific |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse C22orf28 |
Uniprot ID: | Q99LF4 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 55 kDa / 55 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 700-1: 2000 | heart, brain |
Background
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs . Essential during post-implantation development of embryos.
Images
Western blot analysis of RtcB (GB114629) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |