Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CA14 rabbit polyclonal antibody |
Gene Name: | Carbonic anhydrase 14 |
Synonyms: | Carbonate dehydratase XIV, Carbonic anhydrase XIV, CA-XIV, Ca14, Catm |
Immunogen: | Recombinant protein corresponding to Mouse CA14 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 38 kDa |
Observed MW. | 45 kDa |
Uniprot ID: | Q9WVT6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | eye, kidney, liver, lung |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
Images
Western blot analysis of CA14 (GB111553) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |