Your shopping cart is empty!
Anti-CACNA1E Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Voltage-dependent R-type calcium channel subunit alpha-1E |
Synonyms: | BII, Brain calcium channel II, CACH6, CACNA1E, CACNL1A6, Cav2.3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CACNA1E |
Uniprot ID: | Q61290 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 257 kDa / 300 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | brain |
Background
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Images
| Western blot analysis of CACNA1E (GB115237) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
