Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CACNG3 rabbit polyclonal antibody |
Gene Name: | Voltage-dependent calcium channel gamma-3 subunit |
Synonyms: | Neuronal voltage-gated calcium channel gamma-3 subunit, Transmembrane AMPAR regulatory protein gamma-3, Cacng3, calcium channel, TARP gamma-3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CACNG3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 36 kDa |
Observed MW. | 38 kDa |
Uniprot ID: | O60359, Q9JJV5, Q8VHX0 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney, liver |
Background
Calcium Channel gamma-3 is a member of voltage dependent calcium channels (VDCCs) which allows neurons to tailor calcium signaling to functionally discrete cellular regions. Calcium Channel gamma-3 is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. Further, Calcium Channel gamma-3 is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. Calcium Channel gamma-3 gene dysfunction is a susceptibility locus for childhood absence epilepsy.
Images
Western blot analysis of CACNG3 (GB111627) at dilution of 1: 1000 Lane 1: 293T cell lysate Lane 4: Mouse brain tissue lysate Lane 5: Mouse kidney tissue lysate Lane 6: Mouse liver tissue lysate Lane 7: Rat brain tissue lysate Lane 8: Rat kidney tissue lysate Lane 9: Rat liver tissue lysate |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |