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Anti-CAMK2B Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CAMK2B rabbit polyclonal antibody |
Gene Name: | Calcium/calmodulin-dependent protein kinase type II subunit beta |
Synonyms: | CaM kinase II subunit beta, CaMK-II subunit beta, Camk2b, Camk2d |
Immunogen: | Recombinant protein corresponding to Mouse CAMK2B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 60 kDa |
Observed MW. | 60 kDa |
Uniprot ID: | Q13554, P28652, P08413 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 600 | HeLa, SH-SY5Y, U-251MG, Neuro2A, PC-12 |
Background
CaMKII beta (Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAMK2B, CAM2 or CAMKB, belongs to the protein kinase super family, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a member of the NMDAR signaling complex in excitatory synapses, it may functions autonomously after Ca2+ calmodulin binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.
Images
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Western blot analysis of Camk2b (GB111070) at dilution of 1: 300 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
