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Anti-CARD14 Rabbit pAb (100 μl)
| Reactivity: | H,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Caspase recruitment domain-containing protein 14 |
Synonyms: | BIMP2, CARMA2, PSORS2, Bcl10 interacting MAGUK protein 2, PSS1, PRP |
Immunogen: | Recombinant protein corresponding to Mouse CARD14 |
Uniprot ID: | Q99KF0 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 113 kDa / 114/130 kDa |
Product Usage Information
WB | Human, Rat | 1: 500-1: 800 | placenta |
Background
Acts as a scaffolding protein that can activate the inflammatory transcription factor NF-kappa-B and p38/JNK MAP kinase signaling pathways. Forms a signaling complex with BCL10 and MALT1, and activates MALT1 proteolytic activity and inflammatory gene expression. MALT1 is indispensable for CARD14-induced activation of NF-kappa-B and p38/JNK MAP kinases. May play a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis.
Images
| Western blot analysis of CARD14 (GB114514) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
