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Anti-CBP80 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CBP80 rabbit polyclonal antibody |
Gene Name: | Nuclear cap-binding protein subunit 1 |
Synonyms: | 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit, Ncbp1, Cbp80, MGC2087, Sto1, NCBP |
Immunogen: | Recombinantproteincorresponding to Mouse CBP80 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. | 92 kDa |
Observed MW. | 92 kDa |
Uniprot ID: | Q09161, Q3UYV9, Q56A27 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1:500-1:1000 | testis, lymph node |
IHC/IF | Human, Mouse, Rat | 1:600-1:1200 | brain, testis |
Background
Nuclear cap binding protein subunit 1, 80kDa is a subunit of a cap-binding protein complex (CBC) that consists of a CBP20 subunit, which binds the cap, and a NCBP1 subunit, which ensures high-affinity cap binding. The CBC complex may play a role in pre-mRNA recognition and splicing.May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
Images
| Western blot analysis of NCBP1 (GB111665) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse brain using NCBP1 (GB111665) at dilution of 1: 600 (300x lens) |
 | Immunofluorescence of paraffin embedded rat testis using NCBP1 (GB111665) at dilution of 1: 600 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
