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| Reactivity: | M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CCR8 rabbit polyclonal |
Gene Name: | C-C chemokine receptor type 8 |
Synonyms: | CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1, Ccr8,CKRL1, CCR-8, C C chemokine receptor type 8 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CCR8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 40 kDa |
Observed MW. | 40kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 300-1: 600 | brain |
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
Images
| Western blot analysis of CCR8 (GB113737) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
