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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CCT2 rabbit polyclonal antibody |
Gene Name: | T-complex protein 1 subunit beta |
Synonyms: | TCP-1-beta, CCT-beta, Cct2, Cctb |
Immunogen: | Recombinant protein corresponding to Human CCT2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 57 kDa |
Observed MW. | 57 kDa |
Uniprot ID: | P78371, P80314, Q5XIM9 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, testis, ovary |
IHC/IF | Human, Mouse, Rat | 1: 100-1: 800 | brain, ovarian cancer, testis |
Background
This protein component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
Images
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Western blot analysis of TCPB (GB111032) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded human ovarian cancer using TCPB (GB111032) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using TCPB (GB111032) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using TCPB (GB111032) at dilution of 1: 400 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using TCPB (GB111032) at dilution of 1: 400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
