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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Neprilysin |
Synonyms: | Atriopeptidase, Enkephalinase, SFE, CD10, Neutral endopeptidase 24.11, NEP, Neutral endopeptidase, Skin fibroblast elastase, Mme |
Immunogen: | Recombinant protein corresponding to Human CD10 |
Uniprot ID: | P08473 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 85 kDa / 90-110 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, kidney, placenta |
IHC/IF | Human, Mouse, Rat | 1: 800-1: 1600 | breast cancer, kindey, liver, placenta, small intestine |
Background
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.
Images
| Western blot analysis of CD10 (GB114689) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human breast cancer using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human kindey using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human liver using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded human placenta using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse kindey using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse liver using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse placenta using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded mouse small intestine using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat kindey using CD10 (GB114689) at dilution of 1: 800 |
| Immunohistochemistry analysis of paraffin embedded rat liver using CD10 (GB114689) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
