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| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CD13 rabbit polyclonal |
Gene Name: | Aminopeptidase N |
Synonyms: | ANPEP, APN, CD13, GP150, LAP1, P150, PEPN, alanyl aminopeptidase |
Immunogen: | Recombinant protein corresponding to Mouse CD13 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 500-1: 1000 | Colon |
IF | Rat | 1: 1000-1: 2000 | Colon |
Background
Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization.
(Microbial infection) Acts as a receptor for human coronavirus 229E/HCoV-229E. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein . Mediates as well human cytomegalovirus (HCMV) infection .
Images
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Immunohistochemistry analysis of paraffin-embedded rat colon using CD13(GB11356) at dilution of 1:1000. |
| Immunofluorescence of paraffin embedded rat colon using CD13 (GB11356) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
