Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CD2AP rabbit polyclonal antibody |
Gene Name: | CD2-associated protein |
Synonyms: | Mesenchyme-to-epithelium transition protein with SH3 domains 1, METS-1, Cd2ap, Mets1 |
Immunogen: | Recombinant protein corresponding to Mouse CD2AP |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 70 kDa |
Observed MW. | 75-80 kDa |
Uniprot ID: | Q9Y5K6, Q9JLQ0, F1LRS8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, kidney, brain |
Background
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Images
Western blot analysis of CD2AP (GB111396) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |