Reactivity: | M & H,M |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CD30 rabbit polyclonal antibody |
Gene Name: | Tumor necrosis factor receptor superfamily member 8 |
Synonyms: | CD30L receptor, Lymphocyte activation antigen CD30, CD30, Tnfrsf8 |
Immunogen: | Recombinant protein corresponding to Mouse CD30 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P28908, Q60846, P97525 |
Images
Applications | Species | Dilution | Positive tissue |
IHC | Human, Mouse, Rat | 1: 500-1: 1000 | lymph node, spleen |
Background
CD30 is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor super family. CD30 expression is found on activated T and B cells. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. CD30 is useful in diagnosis of classic Hodgkin's lymphoma, anaplastic large cell lymphoma and embryonal carcinoma.
Images
Immunohistochemistry of paraffin embedded human lymph node using CD30 (GB111140) at dilution of 1:600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lymph node using CD30 (GB111140) at dilution of 1:600 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse spleen using CD30 (GB111140) at dilution of 1:600 (400x lens) |
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Immunohistochemistry of paraffin embedded rat lymph node using CD30 (GB111140) at dilution of 1:600 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |