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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | CD44 antigen |
Synonyms: | CD44, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP-1, PGP I, Pgp1, Phagocytic glycoprotein I |
Immunogen: | Human recombinant CD44 protein expressed in HEK293 cells |
Uniprot ID: | P16070 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Product Usage Information
IHC/IF | Human | 1: 600-1: 1800 | lung adenocarcinoma, endometrial carcinoma, pancreas |
Background
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
Images
| Immunohistochemistry analysis of paraffin embedded human endometrial carcinoma using CD44 (GB122054) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin embedded human lung adenocarcinoma using CD44 (GB122054) at dilution of 1: 1800 |
| Immunohistochemistry analysis of paraffin embedded human pancreas using CD44 (GB122054) at dilution of 1: 1800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
