Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CD6/T12 rabbit polyclonal |
Gene Name: | T-cell differentiation antigen CD6 |
Synonyms: | CD6, CD6 molecule, T12, TP120, OX52, FLJ44171, CD6 antigen Tp120, |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CD6/T12 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 72 kDa |
Observed MW. | 120 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 300-1: 800 | CD6 |
Background
CD6 is a type I membrane protein expressed by thymocytes, mature T cells, a subset of B cells known as B1 cells, and some cells in the brain. CD6 is a member of the scavenger receptor cysteine rich (SRCR) family of proteins, which includes the leukocyte antigen CD5. The extracellular domain of CD6 is composed of three SRCR domains and has the same domain organization as CD5. The ligand for CD6 is CD166 also known as activated leukocyte cell adhesion molecule. Through its interaction with CD166 in the thymus, CD6 may have a role in T cell development.
Images
Western blot analysis of CD6 (GB113398) at dilution of 1: 800 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |