Anti-CDKN2A/p16INK4a Mouse mAb (100 μl)

Anti-CDKN2A/p16INK4a Mouse mAb (100 μl)

Brand: ServiceBio
Cat. #: GB121605-100
Availability: In Stock
$259.00
-+
Reactivity: H    
Applications: WB    
Host Species: Mouse    
Clonality: Monoclonal    
Gene Name:

Cyclin-dependent kinase inhibitor 2A

Synonyms:

Cyclin-dependent kinase 4 inhibitor A, CDK4I, CDKN2A, MTS1, CDKN2 , Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16INK4A, p16-INK4

Immunogen:

KLH conjugated Synthetic peptide corresponding to Human P16

Uniprot ID:

P42771

Isotype:

IgG1,k

Purity:

Affinity purification

Predicted MW. / Observed MW.

16 kDa / 16 kDa




Product Usage Information

WB

Human

1: 500-1: 1000

HeLa, 293T




Background

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.




Images

01 GB121605_CDKN2Ap16INK4a_WB.jpg-WM.png

WB analysis of CDKN2Ap16INK4a(GB121605).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4°C overnight.
Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 3000, RT, 1h




Storage

Storage            Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer            PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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