Reactivity: | H |
Applications: | WB |
Host Species: | Mouse |
Clonality: | Monoclonal |
Gene Name: | Cyclin-dependent kinase inhibitor 2A |
Synonyms: | Cyclin-dependent kinase 4 inhibitor A, CDK4I, CDKN2A, MTS1, CDKN2 , Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16INK4A, p16-INK4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human P16 |
Uniprot ID: | P42771 |
Isotype: | IgG1,k |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 16 kDa / 16 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | HeLa, 293T |
Background
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Images
WB analysis of CDKN2Ap16INK4a(GB121605). |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |