Anti-CIAO1 Rabbit pAb (100 μl)

Anti-CIAO1 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB113984-100
Availability: In Stock
$259.00
-+
Reactivity: M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

CIAO1 rabbit polyclonal antibody

Gene Name:

Probable cytosolic iron-sulfur protein assembly protein CIAO1

Synonyms:

CIA1, CIAO1, WDR39

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse CIAO1

Isotype:

IgG

Purity:

Affinity purification

Predicted MW.

38 kDa

Observed MW.

43 kDa

Uniprot ID:

Q99KN2




Product Usage Information

Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

brain




Background

CIAO1, also named as CIA1 or WDR39, is a essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. CIAO1 seems to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation. It may also play a role in chromosome segregation.Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins .As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors.





Images

Western blot analysis of CIAO1 (GB113984) at dilution of 1: 1000




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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