Reactivity: | M,R & M |
Applications: | WB & ICC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Cyclin-dependent kinase 2-interacting protein |
Synonyms: | Cinp, MGC849 |
Immunogen: | Recombinant protein corresponding to Mouse CINP |
Uniprot ID: | Q9D0V8 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 24 kDa / 24 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | brain |
ICC/IF | Mouse | 1: 100-1: 400 | NIH-3T3 |
Background
The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants.
Images
Western blot analysis of CINP (GB114039) at dilution of 1: 600 | |
Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using CINP(GB114039) at dilution of 1: 100-1: 400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |